Skip Navigation Links

» Mukteswar Campus

Scientist Profile

Dr. D. MUTHUCHELVAN
M.V.Sc. PhD, Postdoc (USA)
Senior Scientist,
Virology Division,

Telephone: 05942-286346 Ext. 4005
Mobile No.: +91-9690576511

Field of Specialization Veterinary Virology with special interest in RNA viruses and Reverse genetics Total Research Papers 35
No. Patents Granted / Filed 1 Total No. of Book / Manual 5
No. of M.V.Sc. Student Guided 5 No. of PhD Student Guided 2
Present Number of M.V.Sc. Student 1 Present Numberof PhD Student 1

Top 10 Research Papers

  • Pandey A, Sahu AR, Wani SA, Saxena S, Kanchan S, Sah V, Rajak KK, Khanduri A, Sahoo AP, Tiwari AK, Mishra B, Muthuchelvan D, Mishra BP, Singh RK, Gandham RK. Modulation of Host miRNAs Transcriptome in Lung and Spleen of Peste des Petits Ruminants Virus Infected Sheep and Goats. Front Microbiol. 2017 Jun 26;8:1146. doi: 10.3389/fmicb.2017.01146.
  • Sahu AR, Wani SA, Saminathan M, Rajak KK, Sahoo AP, Pandey A, Saxena S, Kanchan S, Tiwari AK, Mishra B, Muthuchelvan D, Singh RP, Singh Y, Baig M, Mishra BP, Singh RK, Gandham RK. Genome sequencing of an Indian peste des petits ruminants virus isolate, Izatnagar/94, and its implications for virus diversity, divergence and phylogeography. Arch Virol. 2017 Jun;162(6):1677-1693. doi: 10.1007/s00705-017-3288-2.
  • Manjunath S, Mishra BP, Mishra B, Sahoo AP, Tiwari AK, Rajak KK, Muthuchelvan D, Saxena S, Santra L, Sahu AR, Wani SA, Singh RP, Singh YP, Pandey A, Kanchan S, Singh RK, Kumar GR, Janga SC. Comparative and temporal transcriptome analysis of peste des petits ruminants virus infected goat peripheral blood mononuclear cells. Virus Res. 2017 Feb 2;229:28-40. doi: 10.1016/j.virusres.2016.12.014.
  • Kumar R, Rajak KK, Chandra T, Muthuchelvan D, Saxena A, Chaudhary D, Kumar A, Pandey AB. Sequence-based comparative study of classical swine fever virus genogroup 2.2 isolate with pestivirus reference strains. Vet World. 2015 Sep;8(9):1059-62. doi: 10.14202/vetworld.2015.1059-1062.
  • Parida S, Muniraju M, Mahapatra M, Muthuchelvan D, Buczkowski H, Banyard AC. Peste des petits ruminants. Vet Microbiol. 2015 Dec 14;181(1-2):90-106. doi: 10.1016/j.vetmic.2015.08.009. 6: Raut SD, Rajak KK, Kumar R, Singh VK, Saxena A, Chaudhary D, Muthuchelvan D, Pandey AB. Characterization of cytopathogenicity of classical swine fever virus isolate induced by Newcastle disease virus. Virusdisease. 2015 Jun;26(1-2):70-6. doi: 10.1007/s13337-015-0253-0.
  • Raut SD, Rajak KK, Kumar R, Singh VK, Saxena A, Chaudhary D, Muthuchelvan D, Pandey AB. Characterization of cytopathogenicity of classical swine fever virus isolate induced by Newcastle disease virus. Virusdisease. 2015 Jun;26(1-2):70-6. doi: 10.1007/s13337-015-0253-0.
  • Mohandas SS, Muthuchelvan D, Pandey AB, Biswas SK, Chand K, Venkatesan G, Choudhary D, Ramakrishnan MA, Mondal B. Development of reverse transcription loop mediated isothermal amplification assay for rapid detection of bluetongue viruses. J Virol Methods. 2015 Sep 15;222:103-5. doi: 10.1016/j.jviromet.2015.06.005.
  • Santhamani R, Venkatesan G, Minhas SK, Shivachandra SB, Muthuchelvan D, Pandey AB, Ramakrishnan MA. Detection and characterization of atypical capripoxviruses among small ruminants in India. Virus Genes. 2015 Aug;51(1):33-8. doi: 10.1007/s11262-015-1206-9.
  • Dashprakash M, Venkatesan G, Ramakrishnan MA, Muthuchelvan D, Sankar M, Pandey AB, Mondal B. Genetic diversity of fusion gene (ORF 117), an analogue of vaccinia virus A27L gene of capripox virus isolates. Virus Genes. 2015 Apr;50(2):325-8. doi: 10.1007/s11262-015-1172-2.
  • Muthuchelvan D, De A, Debnath B, Choudhary D, Venkatesan G, Rajak KK, Sudhakar SB, Himadri D, Pandey AB, Parida S. Molecular characterization of peste-des-petits ruminants virus (PPRV) isolated from an outbreak in the Indo-Bangladesh border of Tripura state of North-East India. Vet Microbiol. 2014 Dec 5;174(3-4):591-595. doi: 10.1016/j.vetmic.2014.10.027.

Technologies Developed

  • Improved antigen capture ELISA for PPRV
  • RT-LAMP assay for PPR and BT
  • PPR-Pox combined vaccines

Awards

  • Awarded with “Prof. P.K.Uppal Promising Young Scientist Award” In: International seminar on future of livestock health: A paradigm change to maximize productivity for economic gains and XXVI annual convention of Indian Association of Veterinary Microbiologists, Immunologists and specialists in infectious diseases held from 6-8th Sept. 2012 at TANUVAS, Chennai.
  • Best Poster Award In: International seminar on future of livestock health: A paradigm change to maximize productivity for economic gains and XXVI annual convention of Indian Association of Veterinary Microbiologists, Immunologists and specialists in infectious diseases held from 6-8th Sept. 2012 at TANUVAS, Chennai.
  • Dr. C.M. Singh Best Research Paper Award Presented to Dadas R.C., Muthuchelvan, D., Pandey, A.B., Rajak, K.K. Sudhakar, S.B., Shivchandra,S.B. and Venkatesan, G. for the paper entitled Development of loop-mediated isothermal amplification (LAMP) assay for rapid detection of peste des petits ruminant virus (PPRV) genome from clinical samples published in Indian Journal of Comparative Microbiology, Immunology and Infectious Diseases Vol. 33 (1&2): 7-13 by Indian Association of Veterinary Microbiologists, Immunologists and Specialists In Infectious Diseases.
  • Best Oral presentation Award for the paper to Z. Ahmad, K. K. Rajak, D. Muthuchelvan, R. Kumar, D. Chaudhary, R. K. Singh and A. B. Pandey (2014): entitled, “Genetic characterization of Peste-des-petits ruminants viruses based on F and N genes” during 28th Annual Convention of IAVMI held on Oct. 30th – Nov. 1st, 2014 at DUVASU, Mathura (UP)
  • Recipient of MD WISE International Fellowship awarded by Lahey Clinic Medical foundation, Boston, MA USA for the advancement of Medical research from Dec. 2005-Aug.2010

Membership

  • Life Member Indian Society of Veterinary Microbiologists and Immunologists (I.A.V.M.I.)
  • Life Member Veterinary Council of India (VCI).
  • Life member Indian Virological Society

Ongoing Projects

  • Understanding the immune mechanism of host disease resistance and development of marker vaccines and DIVA tests for Peste des Petits Ruminants (PPR).
  • ICAR-CRP on vaccine and diagnostics sub project 8: Development of improved ELISAs for PPR by employing recombinant antigen(s).
  • ICAR- Flagship-Host Pathogen project: A comparative study of the cytokines induced by peste-des-petits-ruminants viral proteins N, P, C and V derived from virulent and vaccine viruses.
  • Understanding the immune mechanism of host disease and development of marker vaccines and DIVA test for Peste des Petits ruminants
  • Understanding the molecular basis of Peste-des-Petits Ruminants virus (PPRV) mediated host immune modulation for the development of next generation vaccine
  • Serosurveillance, isolation and molecular characterization of bluetongue virus in sheep and goats of Tripura and Assam states
  • Supply and Evaluation of experimental PPR vaccine, diagnostic service and maintenance of virus/serum repository.
  • : Serosurveillance and Molecular epidemiology of Peste des petits ruminants (PPR), Sheeppox and Goatpox in sheep and goats of Tripura and Mizoram states.

© 2014 reserved with IVRI