Genome Analysis Laboratory
The lab was established in Division of Veterinary Public Health after large epidemic of JE in the state of Uttar Pradesh in the year 2005 which claimed more than 1000 human lives. Since its inception, the JE lab is involved in development of rapid and reliable diagnostics besides deciphering the epidemiology of JE in different agro-climatic zones of India. The lab provides diagnostic services of JE to Animal Husbandry Departments of various states through CADRAD.The timely detection of JE virus using in-house developed diagnostics in swine population of different states of the country, have helped authorities to take suitable measures to prevent transmission of virus to humans. As a result lives of several children were saved from the deadly JE virus.
Thematic area of lab
Livestock Genomics
Infrastructure and facility in lab
- Real Time PCR
- Gradient PCR
- Electrophoresis assembly
- Centrifuge
- -20 refrigerators
- Weighing balance
- Gel rocker
- Incubators
- Distillation assembly
- Laminar flow
- Oven
- Magnetic stirrer
- Western blotter
- Thermal cycler
- Electroporator
- Shaker incubator
- BOD Incubator
- Trans-illuminator
Major Achievement of Lab
- Studied the genetic basis of resistance to Theileria annulata infection in crossbred, Tharparkar cattle and buffaloes for the first time in India, in the DST FAST-TRACK young scientist project as a PI (2013-16).
- Our team could precisely estimate the breed composition of Vrindavani and Frieswal crossbred cattle with the help of bovine 50K SNP chip data for the first time in India in the institute project (2016-18)
- Recently, identified breed-specific SNPs with intermediate minor allele frequencies that facilitated accurate breed assignment of Indian Tharparkar cattle.
- As a pilot study, we have scanned for selection signature regions with the help of BovineSNP50 chip data, which revealed candidate genes for adaptation and production traits in a variety of cattle breeds
List of projects going on in lab
- Identification of unique signatures of selective sweeps in indigenous dairy cattle breeds
Name and contact details of Lab in-charge
- Dr. Manjit Panigrahi
Senior Scientist, IVRI, Izatnagar